IC-Based Neuro-Stimulation Environment for Arbitrary Waveform Generation

Electrical stimulation of the nervous system is commonly based on biphasic waveforms, which limits its relevance for some applications, such as selective stimulation. We propose in this paper a stimulator capable delivering arbitrary waveforms to electrodes, and suitable non-conventional strategies. Such enables vivo protocols with optimized efficacy or energy efficiency. The designed comprises High Voltage CMOS ASIC generating configurable stimulating current, driven by digital circuitry implemented FPGA. After fabrication, were characterized tested; they successfully generated programmable frequential content up 1.2 MHz voltage compliance between [?17.9; +18.3] V. not optimum when compared single application stimulators, but no embedded literature offers an equivalent bandwidth allows wide range paradigms, including high-frequency blocking consider that will help test unconventional can be used generate proof-of-concept data before designing implantable application-dedicated stimulators.